LAZEN International Zebrafish and Medaka Conference,
29 March – 02 April 2020- Cusco, Perú
Official Website: http://lazen.fcien.edu.uy/events/vi-lazen-symposium—cusco-2020
Day 1 – SUNDAY 29 March – Paraninfo UNSAAC and Cusco Municipal Theater
09:00 – 15:00 OPTIONAL: Tour of Cusco’s nearby archaeological sites
12:00 – 17:00 Registration (Paraninfo UNSAAC)
17:00 – 17:30 Welcome to LAZEN Perú 2020 (at the Municipal Theater)
17:30 – 18:10 ** PUBLIC OPENING LECTURE: Using Human Patients as a Platform for Discovery of Novel Developmental Genes **
Monte Westerfield, University of Oregon, USA
18:30 – 21:00 Welcome reception – musical show by PromPerú
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Day 2 – MONDAY 30 March – Paraninfo UNSAAC
08:00 – 09:00 Registration (ongoing all day)
09:00 – 09:50 Career Development Workshop / Technical Talks (concurrent)
09:50 – 10:10 LAZEN Practical Course Presentations
10:10 – 10:30 Coffee break
10:30 – 11:10 ** THE MOD KEYNOTE LECTURE: Establishment of Oocyte Polarity in Vertebrates **
Mary Mullins, University of Pennsylvania, USA
ORAL SESSION 1: GAMETOGENESIS AND FERTILIZATION
TBA, Chair, Inst
11:10 – 11:30 Han Wang, Soochow University, China
Circadian orchestration of spermatogonial differentiation and fertilization through retinoic acid signaling
11:30 – 11:45 Minoru Tanaka, Nagoya University, Japan
How do germline stem cells initiate oogenesis in Medaka? – the mechanism of sexual fate decision in germ cells –
11:45 – 12:00 Juan Fernandino, Instituto Tecnológico de Chascomús, Argentina
Embryonic germ stem cell type II proliferation is crucial to reproductive success in both sexes and mating behavior of male
12:00 – 12:15 Ricardo Fuentes, Universidad de Concepción, Chile
A zebrafish large-scale forward genetic screen identifies Spotty as a regulator of vertebrate centrosome elimination
12:15 – 12:30 Noriyoshi Sakai, National Institute of Genetics, Japan
Regulation of the ribosome by a germ granule component, Meioc, for differentiation of spermatogonial stem cells in zebrafish
12:30 – 14:00 Lunch break
ORAL SESSION 2: GASTRULATION AND NEURULATION
TBA, Chair, Inst
14:00 – 14:15 Miguel Concha, Universidad de Chile, Chile
Apical tethers stemmed from epithelial delamination guide the movement of organ progenitors in zebrafish
14:15 – 14:30 Thomas Dickmeis, Karlsruhe Institute of Technology, Germany
Regulation of cholesterol biosynthesis by the glucose-sensing transcription factor MondoA is required for zebrafish epiboly
14:30 – 14:45 Javier Méndez, Universidad Nacional Autónoma de México, Mexico
Reactive oxygen species participate in the regulation of E-cadherin dynamics and cell motility in zebrafish epiboly
14:45 – 15:00 Lucía Veloz, Universidad de la República, Uruguay
Role of MARCKS-Like 1a protein during zebrafish neurulation
15:00 – 15:40 ** KEYNOTE LECTURE: Epigenetic Changes in the Genome during Early Development of Medaka **
Hiroyuki Takeda, University of Tokyo, Japan
15:40 – 16:00 Coffee break
16:00 – 16:40 ** KEYNOTE LECTURE: Mechanisms of Gastrulation in Zebrafish **
Lilianna Solnica-Krezel, Washington University in St. Louis, USA
ORAL SESSION 3: MORPHOGENESIS, PATTERNING AND ORGANOGENESIS
TBA, Chair, Inst
16:40 – 16:55 Kiyoshi Naruse, National Institute for Basic Biology, Japan
What are the leucophores in Medaka?
16:55 – 17:10 Paola Lepanto, Institut Pasteur Montevideo, Uruguay
Studying cilia-associated factors that affect adipose tissue development in zebrafish larvae
17:10 – 17:25 Lázaro Centanin, Heidelberg University, Germany
Interplay of lineages during pattern formation and stem-cell driven growth
17:25 – 17:40 Toru Kawanishi, University of Tokyo, Japan
Coordinated growth of multiple tissues during zebrafish body axis elongation
17:40 – 18:10 Flash Talks
18:30 – 21:00 Evening mixer at the Casa de la Cultura Museum- musical show by the Cusco Municipality
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Day 3 -TUESDAY 31 March – Paraninfo UNSAAC
09:00 – 10:30 Poster session 1 (coffee/snacks served at 10:00)
10:30 – 11:10 ** THE EMBO KEYNOTE LECTURE: Biological Robustness: genetic compensation and transcriptional adaptation **
Didier Stainier, Max Planck Institute for Heart and Lung Research, Germany
ORAL SESSION 4: GENE EXPRESSION AND REGULATION
TBA, Chair, Inst
11:10 – 11:30 Robert Geisler, Karlsruhe Institute of Technology, Germany
Archiving and phenotyping of zebrafish lines at the European Zebrafish Resource Center (EZRC)
11:30 – 11:45 Juan Ramón Martínez-Morales, Centro Andaluz de Biología del Desarrollo, Spain
Analysis of the genetic programs activated by Yap during early morphogenesis in teleosts
11:45 – 12:00 Miguel Moreno-Mateos, Centro Andaluz de Biología del Desarrollo, Spain
CRISPR-Cas13d induces efficient mRNA knock-down in animal embryos
12:00 – 12:15 Ariel Bazzini, Stowers Institute for Medical Research, USA
Translation of small open reading frames in 3’ UTRs enhances translation of their canonical open reading frames
12:15 – 12:30 Diana Castañeda Cortés, Instituto Tecnológico de Chascomús, Argentina
Crossover between stress and thyroid hormone axes in stress-induced sex reversal
12:30 – 14:00 Lunch break
ORAL SESSION 5: GENETICS, GENOMICS AND EVOLUTION
TBA, Chair, Inst
14:00 – 14:15 Miguel Allende, Universidad de Chile, Chile
Telling a tale of tails: The Hox13 genes and the specification of the posterior vertebrae and tail in the zebrafish
14:15 – 14:30 Lucía Franchini, Instituto de Investigaciones en Ingeniería Genética y Biología Molecular, Argentina
Regulatory regions and human evolution: linking mutations and phenotypic effects
14:30 – 14:45 Joaquín Letelier, Universidad Mayor, Chile
Shaping fins and limbs: deeply conserved developmental programs
14:45 – 15:00 Nicolas Rohner, Stowers Institute for Medical Research, USA
Metabolic adaptation and resilience in cavefish
15:00 – 15:40 ** KEYNOTE LECTURE: Wild sex, hot sex: Mechanisms of sex determination in natural zebrafish **
John Postlethwait, University of Oregon, USA
15:40 – 16:00 Coffee break
16:00 – 16:40 ** KEYNOTE LECTURE: Neural identity, connectivity and activity of a left-right asymmetric pathway in the zebrafish brain **
Marnie Halpern, Dartmouth College, USA
ORAL SESSION 6: HEART, BLOOD AND IMMUNITY
TBA, Chair, Inst
16:40 – 16:55 Nadia Mercader, University of Bern, Switzerland
Interplay between cardiac regeneration and fibrosis regression in the zebrafish
16:55 – 17:10 Ching-Ling Lien, Children’s Hospital Los Angeles, USA
Heterogeneous pdgfrb+ cells regulate coronary vessel development and revascularization during heart regeneration in zebrafish
17:10 – 17:25 Daniel Cifuentes, Boston University, USA
Uncovering the role of microRNAs in canalizing cell fate determination during hematopoiesis
17:25 – 17:40 Ronald B. Walter, Texas State University, USA
The Medaka (Oryzias latipes) inflammation and immune stress response induced by fluorescent light does not occur upon sunlight exposure and is amplified, but not dependent, on prompts from the eye
17:40 – 18:00 Herman Spaink, Leiden University, The Netherlands
How the microbiome controls the host innate immune system
19:00 – 20:30 Concert at the Cathedral by the Cusco Symphony Orchestra
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Day 4 – WEDNESDAY 1 April
09:00 – 10:30 Poster session 2 (coffee/snacks served at 10:00)
10:30 – 11:10 ** KEYNOTE LECTURE: Vision to Action: How zebrafish detect and catch prey **
Herwig Baier, Max Planck Institute of Neurobiology
ORAL SESSION 7: NEURAL DEVELOPMENT AND PHYSIOLOGY
TBA, Chair, Inst
11:10 – 11:30 Koichi Kawakami, National Institute of Genetics, Japan
The Tol2 transposon technology and its applications to study functional neuronal circuits in zebrafish
11:30 – 11:50 Kristen Kwan, University of Utah, USA
Migratory neural crest regulates optic cup invagination by providing crucial extracellular matrix factors
11:50 – 12:10 Flavio Zolessi, Universidad de la República, Uruguay
Brothers but different: cell polarity and the morphogenesis of retinal ganglion cells and photoreceptors
12:10 – 12:30 David R. Hyde, University of Notre Dame, USA
Comparative transcriptomic and epigenomic approaches reveal mechanisms that regulate zebrafish Müller glia reprogramming and neuronal regeneration
12:30 – 14:00 Lunch break
ORAL SESSION 8: BRAIN DISEASE AND BEHAVIOR
TBA, Chair, Inst
14:00 – 14:20 Edward A. Burton, University of Pittsburgh, USA
Unbiased chemical modifier screens in a zebrafish model in vivo reveal novel small molecule modifiers of tauopathy
14:20 – 14:40 Allan Kalueff, South West University, China
Biological psychiatry of zebrafish
14:40 – 14:55 Jaquelinne Pinheiro-Da-Silva, Universidade Federal do Rio Grande do Norte, Brazil
Zebrafish as an animal model for behavioral studies of fetal alcohol spectrum disorders
14:55 – 15:10 Laura Mazzitelli-Fuentes, Centro Atómico Bariloche, Argentina
Training in a clue-guided maze increases adult neurogenesis in specific pallial circuits
15:10 – 15:50 ** KEYNOTE LECTURE: Seeing is Believing: Using Zebrafish to Decipher the Cellular and Molecular Mechanisms of Peripheral Nerve Regeneration **
Michael Granato, University of Pennsylvania, USA
15:50 – 16:10 Coffee break
16:10 – 16:50 ** THE IUBMB KEYNOTE LECTURE: Imaging Subcellular Dynamics from Molecules to Multicellular Organisms **
Tom Kirchhausen, Harvard University, USA
ORAL SESSION 9: CANCER & IMMUNITY
TBA, Chair, Inst
16:50 – 17:20 Manfred Schartl, University of Würzburg, Germany
Identifying tumor modifier genes and drugs with the transgenic medaka melanoma system
17:20 – 17:35 Alicia McConnell, Harvard University, USA
An encompassing precursor lesion attractor state precedes neural crest reactivation in melanoma
7:35 – 17:50 Carmen G. Feijoo, Universidad Andrés Bello, Chile
T cell-antigen presenting cell interaction in the gut of medaka fish take place at specific areas of the mucosa and is regulated by Ccl25-Ccr9 signaling pathway
17:50 – 18:05 Violeta Kallens, Universidad de Chile, Chile
Zebrafish as a model to study interaction between tumor-associated neutrophils and cancer cells
18:05 – 18:35 ** THE ICGEB KEYNOTE LECTURE: Zebrafish as model for studying gene expression control during embryonic development **
Nora Calcaterra, Universidad Nacional de Rosario, Argentina
18:35 – 18:40 Poster presentation prizes
20:00 – 24:00 Farewell party (venue pending confirmation)
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Day 5 – THURSDAY 2 April
09:00 – 10:30 Zebrafish & Medaka – community sessions / Technical talks (concurrent)
10:30 – 10:50 Coffee break
10:50 – 11:30 ** CLOSING LECTURE: TBA **
Jochen Wittbrodt, Heidelberg University, Germany
11:30 – 12:00 Concluding remarks and farewell
14:00 – 18:00 OPTIONAL: Walking tours of Cusco (museums, markets, churches)
